Coronavirus: Immunity in COVID-19 survivors can last for years, claims study

Rodiano Bonacci
Novembre 22, 2020

Humans make SARS-CoV-2-specific antibodies, CD4+ T cells, and CD8+ T cells in response to SARS-CoV-2 infection.

Lead author author Dr. Muge Cevik of the University of St. Andrews, U.K. said in a statement that the new analysis "provides a clear explanation for why SARS-CoV-2 spreads more efficiently than SARS-CoV and MERS-CoV and is so much more hard to contain".

One of these studies, for instance, found that antibody levels "waned quite rapidly" after infection in the British population, suggesting a risk of multiple infections, Health24 reported. "The spike IgG titers were durable, with modest declines in titers at six to eight months". The researchers said that there was about a 200-fold range in the level of antibody responses among the adults.

In the blood samples, the researchers examined components of immune memory.

Knowing more about factors affecting how far these droplets travel can inform efforts to control their spread, said study co-author Michael Kinzel from UCF.

The researchers also simulated three types of saliva - thin, medium, and thick.

Researchers at the University of Oxford say the findings should give some confidence to the more than 51 million people worldwide who have been infected with the epidemic.

T cells are considered fundamental to define the durability of the immune response after a coronavirus diagnosis as, "T cell memory might reach a more stable plateau, or slower decay phase, later than the first six months post-infection", the study reads.

The study, which has not yet been peer-reviewed, took into consideration various immune facets, including B cells, antibodies and T cells.

In a statement to United Kingdom based Science Media Centre, Stephen Evans, Professor of Pharmacoepidemiology, London School of Hygiene & Tropical Medicine, said that there are two major consequences if the findings are as they say. Most infections do lead to mild disease, especially in middle-aged and younger people.

"Secondly, it is probably very good news for vaccines also being able to provide immunity that is more than very short-term".

"We have solved a major piece of the cytokine storm mystery by characterizing critical factors responsible for initiating this process, and thereby identifying a unique combination therapy using existing drugs that can be applied in the clinic to save lives", Kanneganti said in the news release.

According to a study by frontline health workers fighting the UK's coronavirus epidemic, people who have Covid-19 are more likely to be re-contracted at least six months after their first infection. "But this latest study shows that there is some immunity in those who have been infected".

Staff at Oxford University Hospitals were regularly tested both for Covid-19 infections and for antibodies revealing a past infection.

Altre relazioniGrafFiotech

Discuti questo articolo

Segui i nostri GIORNALE